Posted by: Ticktock | May 4, 2010

Episode 10 FAQ: Vaccine Delivery

If you didn’t catch our two-part vaccine episodes for Podcast Beyond Belief, be sure to check them out and share them with friends and family. They feature Dr. Paul Offit, vaccine expert and author of Autism’s False Prophets: Bad Science, Risky Medicine, and the Search for a Cure and Dr. David Gorski, contributing writer for Science Based Medicine.

Episode 10 features a question from Jim Valentine in Louisville, KY, which we forwarded to our previous guest, Dr. Paul Offit…

What do you think will be the future of vaccine delivery?

I think that actually the richest source of TMB cells, the kind of cells that cause adaptive immunity, are actually in the gut. So, the problem with the gut is that you have to get past the stomach, which produces a lot of protease enzymes that break down proteins, and it produces a lot of acids. It’s actually hard to get the vaccines through the stomach, but I think that’s certainly part of the future.

Another way of giving vaccines – there’s a patch actually that has thousands of very tiny needles, so tiny that you don’t really feel them, that would just be laid onto the skin. Each very small needle has a tiny dose of the vaccine at the end of it so that with the thousands of them you get the entire dose. I think that’s the future.


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